Cryo-EM✗ Internal Only

Cryo-Electron Microscopy and Tomography Center

St. Jude Children's Research Hospital

📍 Memphis, TN · Website ↗

The Cryo-Electron Microscopy and Tomography Center is a shared resource operated by the St. Jude Department of Structural Biology in Memphis. It runs a 300 keV Titan Krios with K3, BioQuantum filter and Volta phase plate, a 200 keV Talos Arctica with K3 and BioQuantum, a Talos L120C for screening, and, since 2024, a cold-FEG Titan Krios G4 with Selectris X and Falcon 4i. Sample preparation uses a Vitrobot Mark IV, a Leica EM GP2, a Gatan Solarus II plasma cleaner and a Pelco easiGlow, with a dedicated GPU cluster and DDN storage.

Cryo-Electron Microscopy and Tomography Center serves its own institution only. These can take outside samples:

Tennessee facilities that take external users

Private providers that run samples

Contact providers directly. We don't broker quotes or pass on your details.

Equipment Inventory(9 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Ted Pella 208C

Ted Pella

Sample Prep
Configuration: Carbon coater

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: Plunge freezer

Leica EM GP2

Leica Microsystems · Vitrification

Sample Prep
Configuration: Automatic plunge freezer

Gatan Solarus II

Gatan · Plasma Cleaner

Sample Prep
Configuration: Plasma cleaner

Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep
Configuration: Glow discharge cleaning

Titan Krios G4

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: Cold FEG (E-CFEG); Selectris X energy filter; Falcon 4i; announced September 2024; 1.2 A capability

Talos Arctica

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 keV; Gatan K3; BioQuantum energy filter

Talos L120C

Thermo Fisher Scientific · Screening / Negative Stain

TEM
Voltage: 120 kV
Configuration: 120 keV; sample screening

Titan Krios G3i

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: 300 kV with a Gatan K3, BioQuantum energy filter and Volta phase plate.