Cryo-EMโœ“ External Access

NanoImaging Services (NIS-WEST, San Diego)

NanoImaging Services

๐Ÿ“ San Diego, CA ยท Website โ†—

NanoImaging Services is a cryo-EM contract research organization founded in 2007 by Bridget Carragher and Clint Potter, with NIS-WEST at 4940 Carroll Canyon Road, San Diego and NIS-EAST in Woburn, Massachusetts. Across the two sites it operates six TEMs, two Titan Krios and four Glacios, with Vitrobot and chameleon vitrification and over 500 CPU cores, 50 GPUs and six petabytes of storage. It acquired the protein production CRO Proteos in 2025 and offers gene-to-structure, single particle analysis and nanoparticle (LNP, EV, AAV, VLP) characterization services.

Equipment Inventory(5 instruments)

Roster verified against the facility's own published instrument list, September 2026.

AKTA go

Cytiva ยท Chromatography

Other
Configuration: Microvolume SEC with Superose 6, Superdex 200 and desalting columns for sample QC

Vitrobot

Thermo Fisher Scientific

Sample Prep
Configuration: At all lab locations; Mark version and count not stated

chameleon

SPT Labtech

Sample Prep
Configuration: Piezo dispensing onto self-wicking nanowire grids; site not stated

Titan Krios

ร—2

Thermo Fisher Scientific

TEM
Configuration: 300 kV G-series; Gatan K3 direct detector, Gatan BioQuantum energy filter, Ceta 16M camera; Volta phase plate on some units; company history dates first Krios to 2017 at Carroll Canyon and a second in 2020

Glacios

ร—4

Thermo Fisher Scientific ยท Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV; Falcon 4 or Falcon 3EC direct detector, Ceta D camera for MicroED; units at both East and West Coast sites; first Glacios 2018, additional 2021