๐Ÿ“ MA40-mile radius7 institutions7 accept external users

Cryo-EM & Mass Spec Facilities Near Boston / Cambridge

The Boston-Cambridge corridor is the densest concentration of cryo-EM and mass spectrometry infrastructure in the US. Harvard, MIT, Boston University, and dozens of biotech companies maintain world-class facilities.

Research Institutions Within 40 Miles

Every institution below is in this directory with an instrument list verified against the facility's own published equipment page. Nearest first.

Private providers that run samples

Companies that run cryo-EM as a paid service: you ship a sample, they prepare grids and collect data, and several also process it.

Contact providers directly. We don't broker quotes or pass on your details.

About Cryo-EM & Structural Biology Near Boston / Cambridge

Boston and Cambridge form the densest cluster of cryo-EM infrastructure in the United States. Harvard Medical School's Cryo-EM Center for Structural Biology on the Longwood campus operates two Titan Krios systems and a Talos Arctica for HMS, Dana-Farber, Boston Children's and MGH researchers, with external access by proposal. MIT's cryo-EM facility supports the Koch Institute and Department of Biology. Boston University has expanded its structural biology capabilities significantly in recent years. The Broad Institute bridges academic and translational cryo-EM, while Dana-Farber provides specialized cancer biology applications. The proximity to hundreds of biotech and pharmaceutical companies in Kendall Square and the Seaport makes this corridor uniquely positioned for industry-academic collaboration in structural biology.

Frequently Asked Questions

How much does cryo-EM cost in Boston?

Academic internal rates in the Boston area typically range from $80-150/hr for a Glacios and $150-250/hr for a Titan Krios. External academic rates are roughly 1.5-2x internal rates. Industry users should expect $250-400/hr depending on the institution.

Can I use Harvard's cryo-EM facility as an external researcher?

Yes. Harvard Medical School's cryo-EM facility accepts external academic and industry users through their core facility service agreement program. Contact the facility directly for current rates and availability.

Which Boston facilities have a Titan Krios?

Harvard Medical School and MIT operate Titan Krios systems, and Boston University's core runs a Glacios 2 that explicitly welcomes external academic users including remote data collection. Several biotech companies in the area also have private Krios installations.