Cryo-EM & Cryo-ET
Data Processing Consulting
Get expert contracting support for structural biology projects. Accelerate your time-to-structure with remote data processing, particle picking, tomogram segmentation, and sub-tomogram averaging.
Our Data Services
Professional contracting for university labs, research institutes, and biotechnology companies.
Single Particle Cryo-EM
End-to-end data processing pipelines from raw movie alignment to high-resolution density maps. Expertise in motion correction, CTF estimation, particle picking, 2D classification, 3D ab-initio reconstruction, refinement, post-processing, and map sharpening in RELION and CryoSPARC.
Cryo-ET & Subtomogram Averaging
Tomogram reconstruction, alignment, and sub-tomogram averaging. Support for automated and manual filament/membrane tracking, particle picking (template matching and deep learning-based approaches), and subtomogram alignment/averaging using PyTom, Dynamo, or custom pipelines.
Software Installation & Setup
Full installation and configuration of Cryo-EM and Cryo-ET software stacks on local workstations, GPU servers, or HPC clusters. Includes RELION, CryoSPARC, IMOD, AreTomo, Dynamo, EMAN2, cisTEM, MotionCor2/3, CTFFIND, and deep-learning tools (Topaz, crYOLO, MemBrain-seg).
Cryo-ET Segmentation & Analysis
Membrane and organelle segmentation of cryo-electron tomograms using deep learning (MemBrain-seg, Dragonfly, IMOD) and manual approaches. Quantitative analysis of segmented volumes including surface area measurements, curvature mapping, and spatial distribution statistics.
Custom Pipelines & Scripts
Custom script development (Python, Bash) to automate data ingestion, transfer, metadata collection, and processing jobs on local GPU workstations or high-performance computing (HPC) clusters.