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Helix BioStructures (cryo-EM services)

Helix Biostructures

📍 Indianapolis, IN · Website ↗

Indianapolis structural biology CRO offering gene-to-structure services: protein production, biophysical characterization, cryo-EM, protein crystallography, X-ray data collection and LNP characterization. Its instruments page names Titan Krios G3i and Glacios cryo-TEMs plus Vitrobot Mark IV, PELCO easiGlow, grid clipping stations, a VolumeScope 2 SEM and an Aquilos 2 FIB/SEM; the August 2025 newsletter states the company runs six Krios and two Glacios microscopes. Data collection is quoted at 5,000 to 15,000 micrographs per day.

Equipment Inventory(8 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Aquilos 2

Thermo Fisher Scientific · Cryo-FIB Milling

FIB-SEM

Gryphon LCP

Art Robbins · Crystallization Robot

Other
Configuration: crystallization robot

Mosquito Xtal3

SPT Labtech · Crystallization Robot

Other
Configuration: crystallization liquid handler

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: count not stated

Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep
Configuration: count not stated

VolumeScope 2

Thermo Fisher Scientific · Serial Block-Face

SEM

Titan Krios

×6

Thermo Fisher Scientific

TEM
Configuration: 300 kV cryo-TEM, six units in the fleet. Detectors and energy filters are not published.

Glacios

×2

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV cryo-TEM, two units in the fleet.