Postdoctoral Position in CryoEM/ET of Virus–Host Interactions – UW–Madison

Postdoctoral Position in CryoEM/ET of Virus–Host Interactions – UW–Madison Madison, United States Application deadline: 02 Oct 2026 A postdoctoral position is available in the Li Lab at the McArdle Laboratory for Cancer Research, University of Wisconsin–Madison, to study HIV-1 and oncoviruses entry and immune recognition using cryoEM/ET methods. Our lab seeks to understand how viral glycoproteins dynamically recognized during receptor engagement and membrane fusion, and how these conformational changes enable viral entry while evading innate and adaptive immune recognition (PMC10686830; PMC11449073; PMC8673750). Current and future projects include HIV-1, KSHV, and EBV, with broader interests in oncogenic viruses and virus–host membrane interfaces. We combine virology and structural biology with advanced imaging approaches, including cryo-electron microscopy (cryoEM), cryo-electron tomography (cryoET), and in situ cryo-FIB/ET, as well as complementary biochemical and computational approaches. Our goal is to visualize dynamic virus-host interactions in native membrane and cellular environments and uncover their molecular mechanisms. UW–Madison provides an outstanding environment for cryo-EM/ET research. The UW-Madison Cryo-Electron Microscopy Research Center (CEMRC) and the NIH-supported Midwest Center for Cryo-Electron Tomography (MCCET) provide state-of-the-art instrumentation and expertise. Candidates with a strong background in cryoEM/ET, particularly in membrane proteins, viruses or membrane associated complexes, are especially encouraged to apply. Salary will be commensurate with experience and follow NIH postdoctoral stipend guidelines. To apply, please send a CV with a brief description of research experience and interests, and the names and contact information of three references by email to Dr. Wenwei Li (wenwei.li@wisc.edu). Madison, United States Postdoctoral Position in CryoEM/ET of Virus–Host Interactions – UW–Madison