Cryo-EMโœ“ External Access

SCSB Cryo-electron Microscopy (Cryo-EM) Laboratory

University of Texas Med Br Galveston

๐Ÿ“ Galveston, TX ยท Website โ†—

The Sealy Center for Structural Biology and Molecular Biophysics cryo-EM laboratory occupies the first floor of UTMB's Medical Research Building and includes the W. M. Keck Center for virus imaging, a BSL-3 containment suite. It operates a 300 kV Titan Krios with a post-column energy filter and direct detector, a 200 kV JEOL JEM-2200FS with in-column omega filter inside BSL-3, and a 200 kV JEOL JEM-2100 for negative stain and training, with a Vitrobot, a Solarus plasma cleaner and a 120-core processing cluster.

Equipment Inventory(6 instruments)

Roster verified against the facility's own published instrument list, September 2026.

HPC Cluster

Custom

Other
Configuration: 120 cores; local EMEN database with remote archival

Vitrobot

Thermo Fisher Scientific

Sample Prep
Configuration: Plunge freezer; generation not stated

Gatan Solarus

Gatan ยท Plasma Cleaner

Sample Prep
Configuration: Plasma cleaner. A vacuum coater is also available.

Titan Krios

Thermo Fisher Scientific

TEM
Configuration: 300 kV; FEG; post-column energy filter; direct electron detector (facility documentation includes a Gatan K2 manual); automated data collection; generation not stated

JEOL JEM-2200FS

JEOL

TEM
Configuration: 200 keV; FEG; in-column omega energy filter; direct electron detector; housed in the W. M. Keck Center BSL-3 suite for infectious pathogens; remote operation over the network

JEOL JEM-2100

JEOL

TEM
Configuration: 200 keV; non-pathogenic specimens, negative stain and user training