Cryo-EM✓ External Access

Structural Biology Core Laboratory (Cryo-EM Facility)

University of Texas Health Science Center

📍 San Antonio, TX · Website ↗

The Structural Biology Core Laboratory at UT Health San Antonio, directed by Shaun Olsen with Elizabeth Wasmuth as cryo-EM co-director, combines X-ray crystallography, NMR and a cryo-EM facility opened in 2022. The cryo-EM facility runs a 200 kV Glacios with a Falcon 4 detector and Selectris energy filter, a Vitrobot and a Leica plunge freezer, backed by a 36-GPU computing cluster with 1.5 PB of storage. Grid preparation, screening and data collection are booked through iLab.

Equipment Inventory(6 instruments)

Roster verified against the facility's own published instrument list, September 2026.

HPC Cluster

Custom

Other
Configuration: 36 GPUs; 1.5 PB storage; for cryo-EM image processing

Rigaku MicroMax 007-HF with HyPix 6000HE

Rigaku

Other
Configuration: X-ray crystallography home source; VariMax-VHF optics, Universal Kappa goniometer, Oxford Cryostream 800; Phoenix and Scorpion crystallization robots, Formulatrix Rock Imager 54

Bruker Avance NMR (500 MHz and 700 MHz)

×2

Bruker

Other
Configuration: Avance III 500 MHz and Avance Neo 700 MHz with cryoprobes; Jasco 815 CD spectrometer and Refeyn TwoMP mass photometer also in the core

Vitrobot

Thermo Fisher Scientific

Sample Prep
Configuration: Plunge freezer; generation not stated

Leica EM GP

Leica

Sample Prep
Configuration: Named only as 'Leica Plunge Freezer'; exact model (GP vs GP2) not stated

Glacios

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV; Falcon 4 direct detector; Selectris energy filter; installed 2022 (acquired July 2022, $5M three-year investment); single-particle analysis

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →