Cryo-EM✓ External Access

CryoEM Core (Advanced Technology Cores)

Baylor College of Medicine

📍 Houston, TX · Website ↗

The CryoEM Core is one of Baylor College of Medicine's Advanced Technology Cores, located in the Alkek Building (rooms N006 and N420) and rated BSL-1. It operates a 200 kV Glacios with Autoloader, an Aquilos 2 cryo-FIB with integrated fluorescence microscope, a JEOL JEM-3200FSC with in-column filter and Gatan K2 Summit, a JEOL JEM-2200FS with in-column filter and DE20, a JEOL JEM-2100 with DE12 and a JEOL JEM-1230 for negative stain. Sample preparation includes a Vitrobot, a Leica EM GP, a Leica EM ICE high-pressure freezer and, by arrangement with the Pillon lab, a chameleon.

Equipment Inventory(12 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Aquilos 2

Thermo Fisher Scientific · Cryo-FIB Milling

FIB-SEM
Configuration: Cryo-DualBeam with integrated fluorescence light microscope (iFLM)

Leica EM GP

Leica

Sample Prep
Configuration: Automatic plunge freezer

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: Plunge freezer; policies page names Vitrobot Mark IV

Leica EM ICE

Leica

Sample Prep
Configuration: High pressure freezer; $120 per shot

chameleon

SPT Labtech

Sample Prep
Configuration: Not core-owned; available through arrangement with the Pillon lab

Fischione 1070

Fischione

Sample Prep
Configuration: NanoClean plasma cleaner

Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep
Configuration: Glow discharge

JEOL JEM-2200FS

JEOL

TEM
Configuration: 200 kV FEG; in-column energy filter; phase plate holder with airlock; DE20 direct detector

JEOL JEM-2100

JEOL

TEM
Configuration: 200 kV LaB6; DE12 direct detector; Gatan 4k x 4k CCD

JEOL JEM-1230

JEOL · Screening / Negative Stain

TEM
Configuration: 120 kV; 4k x 4k CCD; negative stain and sections

Glacios

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV X-FEG with autoloader. Detector not published.

JEOL JEM-3200FSC

JEOL

TEM
Configuration: 300 kV FEG; in-column omega energy filter; cryo-chuck for three grids; Gatan K2 Summit

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →