Cryo-EM✓ External Access

Leduc Bioimaging Facility (Brown BioMed Core Facilities)

Brown University

📍 Providence, RI · Website ↗

The Leduc Bioimaging Facility is a Brown BioMed core in Sidney Frank Hall that provides light microscopy, electron microscopy and cryo-EM to the Brown community and outside investigators. Its cryo-EM capability is a Thermo Scientific Tundra 100 kV cryo-TEM with a Falcon C direct detector and semi-automated AutoGrid loader, supported by a Vitrobot Mark IV plunge freezer and an Emitech K100X glow discharger. The facility also runs an Apreo VS serial block-face SEM, several confocal systems and ultramicrotomes.

Equipment Inventory(5 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: Plunge freezer, listed as Vitrobot IV

Emitech K100X

Quorum · Glow Discharge

Sample Prep
Configuration: Glow discharge unit

Leica EM UC7

Leica Microsystems · Ultramicrotome

Sample Prep
Configuration: Ultramicrotome installed 2020

VolumeScope 2

Thermo Fisher Scientific · Serial Block-Face

SEM
Configuration: Serial block-face SEM, listed as Apreo VS

Tundra

Thermo Fisher Scientific · Screening

TEM
Voltage: 100 kV
Configuration: 100 kV X-FEG; Falcon C direct detector; semi-automated loader for up to five AutoGrids; EPU; 50 TB storage; Sidney Frank Hall room 105

Published Rates

As published by the facility, retrieved Aug 10, 2026 · source. Rates change; confirm with the facility before budgeting.

ServiceRateApplies toNotes
Tundra cryo-TEM (additional hours)$31externalacademic
Tundra cryo-TEM (first 4 hours, per hour)$101externalacademic
Training (session)$283internal—
Tundra cryo-TEM (additional hours)$20internal—
Tundra cryo-TEM (first 4 hours, per hour)$64internalBrown / RI academic; FY26
Technical assistance (hourly)$45——