Cryo-EM✓ External Access

Protein Structure, Analysis, & Design (PSAD) Core

University of Iowa

📍 Iowa City, IA · Website ↗

Carver College of Medicine core (formerly the Protein and Crystallography Facility, now the Protein Structure, Analysis, & Design Core) at 51 Newton Rd, Iowa City, offering protein production, biophysical characterization, crystallography and cryo-EM. Its 200 kV Glacios, announced December 2024 and expected fall 2025, is configured with a Falcon 4i camera and Selectris energy filter, with a Vitrobot Mark IV for grid preparation. Negative stain EM is done on a Hitachi HT7800 in the separate Central Microscopy Research Facility, and X-ray and SAXS data are collected remotely at ALS and APS.

Equipment Inventory(2 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep

Configuration: Vitrobot rate $30-85/hr; grid clipping $20-30 per grid

Glacios

Thermo Fisher Scientific · Single Particle / Screening

TEM

Voltage: 200 kV

Configuration: 200 kV; Falcon 4i camera; Selectris energy filter; Ceta-D listed in purchase announcement; announced Dec 2024, anticipated arrival fall 2025; Glacios rate $30-40/hr or $800/day

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →