Cryo-EM✓ External Access

Yale CryoEM Resource (YCR)

Yale University

📍 New Haven, CT · Website ↗

The Yale CryoEM Resource is a university-wide core unified in July 2020 with sites at West Campus, the Yale School of Medicine, and Science Hill. It operates a 300 kV Titan Krios G2 (K3, Falcon 3EC, GIF Quantum LS, Volta phase plate) at West Campus, two 200 kV Glacios instruments (one at YSM with K3 and Volta phase plate, one on Science Hill with K3 and MicroED capability), a Tecnai T12 at YSM, and a Talos L120C on Science Hill. Sample preparation covers three Vitrobot Mark IVs, an SPT Labtech chameleon, glow dischargers, plasma cleaners, and coaters.

Equipment Inventory(9 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Leica EM ACE600

Leica Microsystems · Coater

Sample Prep
Configuration: High vacuum coater, YSM

Vitrobot Mark IV

×3

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: One each at West Campus, YSM, and Science Hill

chameleon

SPT Labtech

Sample Prep
Configuration: Yale School of Medicine site

Gatan Solarus 950

Gatan

Sample Prep
Configuration: Plasma cleaner, YSM

Pelco easiGlow

×2

Ted Pella · Glow Discharge

Sample Prep
Configuration: Glow discharge, West Campus and Science Hill

Glacios

×2

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: YSM-Glacios: 200 kV X-FEG, autoloader, Volta phase plate, Ceta, K3, Sterling Hall of Medicine IE 26. SH-Glacios: 200 kV X-FEG, Ceta-D, K3 Summit, EPU-D MicroED, Yale Science Building C133D

Tecnai T12

Thermo Fisher Scientific

TEM
Configuration: 120 kV LaB6, cryo side-entry holder, Gatan CCD, SerialEM; YSM-Tecnai T12, Sterling Hall of Medicine IE 26

Talos L120C

Thermo Fisher Scientific · Screening / Negative Stain

TEM
Voltage: 120 kV
Configuration: 120 kV LaB6, Ceta CMOS, digital FluCam, SerialEM; SH-Talos L120C, Bass Center room 231

Titan Krios G2

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: 300 kV, X-FEG, three condenser lens system, Volta phase plate, K3 Summit, Falcon 3EC, Ceta2, GIF Quantum LS (model 1967); West Campus ABC room 059F; opened 2017

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →