Cryo-EM✓ External Access

Waitt Advanced Biophotonics Core Facility (BPHO)

Salk Institute

📍 La Jolla, CA · Website ↗

The Waitt Advanced Biophotonics Core is Salk's shared light and electron microscopy facility. Its EM instrumentation is a Zeiss Libra 120 PLUS energy-filtered TEM, a Zeiss Sigma variable pressure FEG SEM, and a Gatan 3View serial block face SEM, with Leica UC7/FC7 ultramicrotomy, Leica EM ICE high pressure freezing, Leica AFS freeze substitution, a Leica EM GP plunge freezer and a Vitrobot. It is a conventional and volume EM core rather than a high-resolution cryo-EM core; Salk's Titan Krios, Talos Arctica and Aquilos cryo-FIB are owned by the Lyumkis Lab.

Equipment Inventory(8 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot

Thermo Fisher Scientific

Sample Prep

Configuration: Mark version not stated

Leica EM AFS

Leica Microsystems · Freeze Substitution

Sample Prep

Configuration: Automatic freeze substitution

Leica EM GP

Leica

Sample Prep

Configuration: Automatic plunge freezer

Leica EM UC7/FC7

Leica Microsystems · Cryo-Ultramicrotome

Sample Prep

Configuration: Ultramicrotome with cryo chamber

Leica EM ICE

Leica

Sample Prep

Configuration: High pressure freezer

Sigma VP

Carl Zeiss

SEM

Configuration: Variable pressure field emission SEM with SE and BSE detectors

Gatan 3View

Gatan

SEM

Configuration: Serial block face SEM with in-chamber ultramicrotome

Zeiss Libra 120 PLUS

Zeiss · Energy-Filtered TEM

TEM

Configuration: 120 kV energy-filtered TEM with 2k x 2k fiber-optically coupled YAG CCD

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →