PhD candidate - Structural Glycoproteomics

PhD candidate - Structural Glycoproteomics Radboud university medical center, Netherlands Application deadline: 17 Aug 2026 Are you passionate about mass spectrometry, informatics, and glycobiology? We are looking for a motivated and ambitious PhD student in our glycoproteomics team to push high-end mass spectrometry hardware and software technologies beyond current limits by developing structural glycoproteomics. For development and translational research we make use of patient samples and models with defined genetic and/or biochemical defects that require structural glycoproteomics for better diagnosis, disease monitoring, and understanding of glycobiology underlying disease. This PhD position is part of "BioBeyond_NL", a project within the NWO National roadmap for Large Scale Research Infrastructures. Within BioBeyond_NL you will collaborate with academic and industrial partners to establish a national infrastructure to unravel biological information beyond the genetic code. You will work closely together with mass spectrometrists, glycobiologists, and computational experts as part of an established R&D team that will train and support you in your project. Your Workplace At Radboudumc, you will work in a highly collaborative, interdisciplinary, and international environment. We are a leading European center for genomic medicine and rare disease research, with strong connections to clinicians, patients, and the academic + industrial analytical chemistry field. What sets us apart is our unique position at the interface of fundamental research on glycoproteomics and translational research on genetic disease applications involving clinicians and patients. This ensures that your work will have clinical relevance and impact. You will join a group that performs (pre-)clinical research on genetic glycosylation disorders aiming to improve diagnostics, understand disease mechanisms and develop treatments. Our team consists of senior scientists, technicians, PhD students, and post-docs with multidisciplinary expertise of glycoproteomics, glycobiology, analytical chemistry, and informatics. The position is based at Radboudumc in Nijmegen, the Netherlands. Radboudumc is internationally renowned for its research and diagnostics on a variety of genetic disorders and the impact of personalized medicine. The position is primarily housed in the department of Human Genetics with a strong collaboration with Bruker Daltonics. Our department offers an exciting working environment with enthusiastic people from many parts of the world, providing ample critical mass and a stimulating, collaborative atmosphere for high quality research. At the department of Human Genetics, you work on the diagnosis and treatment of hereditary disorders in patients and their families. You work in the outpatient clinic or in the laboratory for diagnostic testing, where genetic, metabolic, and neurochemical analyses are performed. In addition, you contribute to research exploring the relationship between genes and disease. As a leading, multidisciplinary department, you provide high quality genetic healthcare and contribute to scientific progress. Your Profile You bring curiosity, creativity, and energy to the team. Proactive and self-driven, you take initiative and thrive in collaborative environments, working effectively with colleagues both within and beyond the department. You are motivated, communicative, hardworking, and adaptable, always keeping the team’s goals and success firmly in focus. Your Profile: Candidates must have completed a MSc degree in Chemistry, Molecular Life Sciences, or a related field. Hands-on experience with mass spectrometry. Experience with chemometrics and informatics (Python programming). Solid theoretical background in molecular and cell biology and experience with glycoproteomics or glycomics will be considered a strong plus. Self-motivated, project-oriented work ethic with collaborative and team player attitude. Effective communication, writing and presentation skills in English for multidisciplinary audience. Plan and perform scientific experiments in an independent manner. Critically analyze data. Report results. Take a leading role in writing manuscripts. Present data at local, national and international scientific meetings. Supervise MSc and/or BSc students. Active participation in group discussions. To find out more and apply, please see here.