Cryo-EM✗ Internal Only

Cryo-Electron Microscopy and Tomography Center

St. Jude Children's Research Hospital

📍 MEMPHIS, TN · Website ↗

The Cryo-Electron Microscopy and Tomography Center is a shared resource operated by the St. Jude Department of Structural Biology in Memphis. It runs a 300 keV Titan Krios with K3, BioQuantum filter and Volta phase plate, a 200 keV Talos Arctica with K3 and BioQuantum, a Talos L120C for screening, and, since 2024, a cold-FEG Titan Krios G4 with Selectris X and Falcon 4i. Sample preparation uses a Vitrobot Mark IV, a Leica EM GP2, a Gatan Solarus II plasma cleaner and a Pelco easiGlow, with a dedicated GPU cluster and DDN storage.

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Equipment Inventory(9 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Ted Pella 208C

Ted Pella

Sample Prep
Configuration: Carbon coater

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: Plunge freezer

Leica EM GP2

Leica Microsystems · Vitrification

Sample Prep
Configuration: Automatic plunge freezer

Gatan Solarus II

Gatan · Plasma Cleaner

Sample Prep
Configuration: Plasma cleaner

Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep
Configuration: Glow discharge cleaning

Titan Krios G4

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: Cold FEG (E-CFEG); Selectris X energy filter; Falcon 4i; announced September 2024; 1.2 A capability

Talos Arctica

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 keV; Gatan K3; BioQuantum energy filter

Talos L120C

Thermo Fisher Scientific · Screening / Negative Stain

TEM
Voltage: 120 kV
Configuration: 120 keV; sample screening

Titan Krios G3i

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: 300 kV with a Gatan K3, BioQuantum energy filter and Volta phase plate.