Cryo-EMโœ“ External Access

Beckman Center for Cryo-Electron Microscopy

University of Pennsylvania

๐Ÿ“ PHILADELPHIA, PA ยท Website โ†—

Located in Krishna P. Singh Center for Nanotechnology. Provides cryo-EM and cryo-ET for high-resolution structural analysis of biological macromolecules. Serves UPenn and greater Philadelphia area.

Equipment Inventory(6 instruments)

Zeiss Crossbeam 550

Zeiss

FIB-SEM

Zeiss LSM 900

Zeiss

Other

Alveole micropatterning

Alveole

Sample Prep

Vitrobot Mark IV

Thermo Fisher Scientific ยท Vitrification

Sample Prep

Titan Krios G3i

Thermo Fisher Scientific ยท Single Particle / Tomography

TEM
Voltage: 300 kV
Detector: K3
Filter: BioQuantum
Internal: $60/hr

Glacios 2

Thermo Fisher Scientific ยท Single Particle / Screening

TEM
Voltage: 200 kV
Detector: Falcon 4i
Filter: Selectris

Published Rates

As published by the facility, retrieved Aug 10, 2026 ยท source. Rates change; confirm with the facility before budgeting.

ServiceRateApplies toNotes
Electron cryo-microscopy (hourly)$120/hrโ€”โ€”
Plunge freezing$125/sampleโ€”โ€”
Single particle data collection (hourly)$100/hrโ€”โ€”
T12 / JEOL 1010 (hourly)$50/hrโ€”โ€”
TF-20 EPU run (24 hr)$1500/24hrโ€”โ€”
TF-20 use (assisted)$125/hrโ€”โ€”
Tomography image construction$450/tomoโ€”dual axis

Pricing

InstrumentInternal RateExternal RateNotes
Titan Krios G3i$60/hrโ€”Instrument use approx $40-$60/hr. Staff time $100-$163/hr depending on service level.