Cryo-EM✓ External Access

Cryo-Electron Microscopy Core

Case Western Reserve University

📍 Cleveland, OH · Website ↗

The Cryo-Electron Microscopy Core at Case Western Reserve University School of Medicine (1819 E 101st Street, Cleveland) is the cryo-EM arm of the Cleveland Center for Membrane and Structural Biology. It operates a 300 kV Titan Krios G3i with BioQuantum K3 and Volta phase plate, a 200 kV Glacios with Selectris energy filter and Falcon 4 detector, an Aquilos 2 cryo-FIB-SEM, a 200 kV Tecnai TF20 and a 120 kV Tecnai G2 Spirit T12. Access is via iLab for trained users and those seeking training.

Equipment Inventory(5 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Aquilos 2

Thermo Fisher Scientific · Cryo-FIB Milling

FIB-SEM
Configuration: cryo-DualBeam FIB-SEM for lamella preparation

Titan Krios G3i

Thermo Fisher Scientific · Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: 300 kV X-FEG; Gatan BioQuantum energy filter with K3; Volta phase plate

Glacios

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV X-FEG; Selectris energy filter (spelled 'Seletrix' on page); Falcon IV direct electron detector

Tecnai F20

Thermo Fisher Scientific

TEM
Configuration: Tecnai TF20, 200 kV FEG; Tietz TemCam-F416 4k CMOS and Direct Electron DE-20

Tecnai T12

Thermo Fisher Scientific

TEM
Configuration: Tecnai G2 Spirit T12, 120 kV; Gatan US4000 4k CCD (Gatan 895)

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →