Cryo-EM✓ External Access

Cryo-EM Facility

Cold Spring Harbor Laboratory

📍 COLD SPRING HARBOR, NY · Website ↗

Cryo-EM core in the Beckman building at Cold Spring Harbor Laboratory on Long Island, operational since January 2018 and open to external academic and non-academic users through iLab. It operates a Titan G3 Krios with Gatan K3 detector, BioQuantum energy filter and phase plate, plus a Talos 120C screening microscope, a Vitrobot and a Leica GP plunger.

Equipment Inventory(4 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot

Thermo Fisher Scientific

Sample Prep

Configuration: double-sided blotting

Leica EM GP

Leica

Sample Prep

Configuration: single-sided blotting

Titan Krios G3

Thermo Fisher Scientific · Single Particle / Tomography

TEM

Configuration: 300 kV, autoloader, Gatan K3 detector, Gatan BioQuantum energy filter, phase plate, installed 2017

Talos L120C

Thermo Fisher Scientific · Screening / Negative Stain

TEM

Voltage: 120 kV

Configuration: 120 kV screening microscope, Gatan cryo holders