Cryo-EMโœ“ External Access

Laboratory for BioMolecular Structure (LBMS)

Brookhaven National Laboratory

๐Ÿ“ UPTON, NY ยท Website โ†—

DOE-funded national cryo-EM user facility at Brookhaven National Laboratory in Upton, New York, with access free of charge through a peer-reviewed proposal process with March 15 and September 15 deadlines. It operates a 300 kV Krios G3i (Empire) with K3 detector and BioQuantum filter, a Talos L120C (Powell) and JEOL JEM-2100F (Stonewall) for screening, and an Aquilos 2 cryo-FIB.

Equipment Inventory(4 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Aquilos 2

Thermo Fisher Scientific ยท Cryo-FIB Milling

FIB-SEM
Configuration: cryo-FIB, integrated sputter coater, fluorescence microscope, NanoManipulator

Titan Krios G3i

Thermo Fisher Scientific ยท Single Particle / Tomography

TEM
Voltage: 300 kV
Configuration: 300 kV, X-FEG, Gatan K3 direct electron detector, BioQuantum energy filter, Ceta 16M camera, nickname Empire

Talos L120C

Thermo Fisher Scientific ยท Screening / Negative Stain

TEM
Voltage: 120 kV
Configuration: 20-120 kV, LaB6, Ceta 16M camera, nickname Powell

JEOL JEM-2100F

JEOL

TEM
Configuration: 80-200 kV, FEG, Gatan US4000 4k x 4k CCD, nickname Stonewall