Cryo-EM✓ External Access

UNC CryoEM Core Facility

University of North Carolina Chapel Hill

📍 CHAPEL HILL, NC · Website ↗

University-wide cryo-EM core (est. 2019) in Glaxo Research Building. Offers SPA, CryoET, and cryo-TEM of nanoparticles (LNPs, VLPs, EVs). Titan Krios G4 arriving Summer 2026.

Equipment Inventory(3 instruments)

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep

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Recommended Consumables

for Vitrobot Mark IV

Whatman #1 Blotting Paper

Ted Pella · via Amazon

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Ethane Gas (Research Grade)

Electron Microscopy Sciences · via Direct

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Vitrobot Filter Paper

Thermo Fisher Scientific · via Direct

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Talos Arctica

Thermo Fisher Scientific · Single Particle / Screening

TEM

Voltage: 200 kV

Detector: Falcon 3EC

Titan Krios G4

Thermo Fisher Scientific · Single Particle / Tomography

TEM

Voltage: 300 kV

Detector: Falcon 4i

Filter: Selectris X

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Recommended Consumables

for Titan Krios G4

R1.2/1.3 Cu 300 Mesh Grids

Quantifoil · via Direct

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C-Flat 1.2/1.3 Holey Carbon Grids

Electron Microscopy Sciences · via Direct

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Compatible Accessories

for Titan Krios G4

AutoGrid Assembly Kit

Thermo Fisher Scientific · via Direct

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Standard Software Protocols

for Titan Krios G4

cryoSPARC License (Academic)

Structura Biotechnology · via Direct

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