Cryo-EM✓ External Access

Shared Materials Instrumentation Facility (SMIF), Duke University

Duke University

📍 DURHAM, NC · Website ↗

Duke's Shared Materials Instrumentation Facility (SMIF) operates two cryo-TEMs: a 300 kV Titan Krios (TEM3) with a 12-grid autoloader, Gatan K3 BioQuantum, Falcon 2 and Ceta 16M cameras and a Volta phase plate, and a 100 kV Tundra (TEM4) with a Ceta camera. Two Vitrobot Mark IV plungers and a PELCO glow discharge unit support grid preparation. The facility is open to external academic and industry users on a fee basis, and the Krios is part of the NIEHS/Duke/UNC Molecular Microscopy Consortium.

Equipment Inventory(5 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot Mark IV

×2

Thermo Fisher Scientific · Vitrification

Sample Prep

Configuration: Two separate units, SMIF codes VITRO1 and VITRO2

Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep

Configuration: SMIF code GLOW1

Titan Krios

Thermo Fisher Scientific

TEM

Configuration: SMIF instrument code TEM3. 300 kV with 12-grid autoloader and Volta phase plate; Gatan K3 with BioQuantum energy filter, Falcon 2 and Ceta 16M; EPU, Latitude and SerialEM.

Tundra

Thermo Fisher Scientific · Screening

TEM

Voltage: 100 kV

Configuration: SMIF code TEM4; 100 kV; Ceta camera with dose fractionation; Smart EPU; semi-automated sample loading

Tecnai T12

Thermo Fisher Scientific

TEM

Configuration: SMIF code TEM2; general-purpose room-temperature TEM, not a cryo instrument

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →