Cryo-EM✓ External Access

RTSF Cryo-EM Facility

Michigan State University

📍 EAST LANSING, MI · Website ↗

Michigan State University's Research Technology Support Facility operates a dedicated cryo-EM core as part of a 15 million dollar expansion of cryo-EM infrastructure. The facility runs a 300 kV Titan Krios G4i for single-particle analysis and cryo-electron tomography alongside a Talos Arctica used for negative stain and cryo-grid screening. It also provides FIB-SEM lamella preparation and a full suite of vitrification and glow-discharge equipment.

Equipment Inventory(5 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Hydra Bio

Thermo Fisher Scientific

FIB-SEM
Configuration: Helios Hydra Bio FIB-SEM used for cryo-lamella preparation.

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep
Configuration: Robotic plunge-freezing system for cryo-EM grid vitrification.

Leica EM GP2

Leica Microsystems · Vitrification

Sample Prep
Configuration: Robotic plunge-freezing system for cryo-EM grid vitrification.

Titan Krios

Thermo Fisher Scientific

TEM
Configuration: 300 kV field emission cryo-TEM with a Falcon 4i camera and Selectris X energy filter, used for single particle analysis and cryo-ET.

Talos Arctica

Thermo Fisher Scientific · Single Particle / Screening

TEM
Voltage: 200 kV
Configuration: 200 kV cryo-TEM with Selectris energy filter and Falcon 4i camera, used for negative stain and initial cryo-grid screening.

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →