Center for Structural Biology Cryo-EM Facility (CCR)
National Cancer Institute
📍 BETHESDA, MD · Website ↗
The CSB Cryo-EM Facility is the NCI Center for Cancer Research intramural cryo-EM core on the Bethesda campus, distinct from the National Cryo-EM Facility (NCEF) at the Frederick National Laboratory, and it primarily serves CSB and CCR investigators with time also available to other NCI and NIH intramural groups after committee review. It operates a 300 kV Titan Krios G4 with cold FEG, Selectris X filter and Falcon 4i, a 200 kV Talos Arctica G2 with BioQuantum K3, a Talos L120C and an Aquilos 2 cryo-FIB-SEM.
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Equipment Inventory(7 instruments)
Roster verified against the facility's own published instrument list, September 2026.
Aquilos 2
Thermo Fisher Scientific · Cryo-FIB Milling
chameleon
SPT Labtech
Vitrobot Mark IV
Thermo Fisher Scientific · Vitrification
Leica EM GP2
Leica Microsystems · Vitrification
Talos Arctica
Thermo Fisher Scientific · Single Particle / Screening
Talos L120C
Thermo Fisher Scientific · Screening / Negative Stain
Titan Krios G4
Thermo Fisher Scientific · Single Particle / Tomography