Cryo-EM✓ External Access

Harvard Cryo-EM Center for Structural Biology (HC2EM)

Harvard University

📍 Cambridge, MA · Website ↗

Joint effort by Harvard Medical School, Dana-Farber, Boston Children's Hospital, and MGH providing state-of-the-art cryo-EM to the local structural biology community.

Equipment Inventory(4 instruments)

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep

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Recommended Consumables

for Vitrobot Mark IV

Whatman #1 Blotting Paper

Ted Pella · via Amazon

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Ethane Gas (Research Grade)

Electron Microscopy Sciences · via Direct

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Vitrobot Filter Paper

Thermo Fisher Scientific · via Direct

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Pelco easiGlow

Ted Pella · Glow Discharge

Sample Prep

Titan Krios

Thermo Fisher Scientific

TEM

Internal: $73/hrExternal: $99/hr

Talos Arctica

Thermo Fisher Scientific · Single Particle / Screening

TEM

Voltage: 200 kV

Detector: Falcon 3EC

Internal: $49/hrExternal: $80/hr

Pricing

Instrument	Internal Rate	External Rate	Notes
Titan Krios	$73/hr	$99/hr	FY26 (eff. July 2025). Internal ~$73/hr. External academic ~$98.66/hr.
Talos Arctica	$49/hr	$80/hr	FY26 (eff. July 2025). Internal ~$48.74/hr. External academic ~$79.77/hr.