Cryo-EM✓ External Access

Harvard Center for Biological Imaging (HCBI)

Harvard University (Cambridge)

📍 CAMBRIDGE, MA · Website ↗

The Harvard Center for Biological Imaging is a Faculty of Arts and Sciences core facility in the LISE building on Harvard's Cambridge campus, separate from the Harvard Medical School cryo-EM center at Longwood. It operates a 200 kV Glacios 2 cryo-TEM with an integrated Falcon 4i direct electron detector, X-FEG source and Selectris energy filter for single-particle analysis, cryo-ET and MicroED. Sample preparation equipment includes a Vitrobot Mark IV, a Wohlwend high-pressure freezer and Leica EM AFS2 freeze-substitution equipment.

Equipment Inventory(2 instruments)

Roster verified against the facility's own published instrument list, September 2026.

Vitrobot Mark IV

Thermo Fisher Scientific · Vitrification

Sample Prep

Configuration: Robotic plunge-freezing system for cryo-EM grid vitrification.

Glacios 2

Thermo Fisher Scientific · Single Particle / Screening

TEM

Voltage: 200 kV

Configuration: 200 kV cryo-TEM with integrated Falcon 4i direct electron detector, X-FEG source, fringe-free imaging and Selectris energy filter, used for single-particle analysis, cryo-ET and MicroED.

Rates

This facility publishes its rates as a document rather than a web page. View the facility's rate document →