Cryo-EM Core (Sanford Burnham Prebys Shared Resources)
Sanford Burnham Prebys Medical Discovery Institute
📍 La Jolla, CA · Website ↗
The Sanford Burnham Prebys Cryo-EM Core in La Jolla operates a 300 kV Thermo Fisher Titan Krios with a Gatan K3 direct detector, a 120 kV Tecnai T12 with an Eagle 4K CCD for negative stain, and a Vitrobot Mark IV. It offers full imaging service, trained user instrument access, and hybrid arrangements to academic and commercial users. Krios data collection is priced per 24 hours (about $1,462 non-profit and $2,848 commercial) with hourly T12, Vitrobot and training rates posted.
Equipment Inventory(3 instruments)
Roster verified against the facility's own published instrument list, September 2026.
Vitrobot Mark IV
Thermo Fisher Scientific · Vitrification
Titan Krios
Thermo Fisher Scientific
Tecnai T12
Thermo Fisher Scientific
Published Rates
As published by the facility, retrieved Aug 10, 2026 · source. Rates change; confirm with the facility before budgeting.
| Service | Rate | Applies to | Notes |
|---|---|---|---|
| Consultation per hour | $87.73 | external | non-profit |
| Krios data collection per 24 hours (full service) | $1,462.05 | external | non-profit; staff does imaging |
| Krios per 24 hours (self-use) | $1,140.58 | external | non-profit |
| Krios screening per hour (full service) | $132.36 | external | non-profit |
| Training per hour | $128.59 | external | non-profit |
| Vitrobot per hour (self-use) | $18.23 | external | non-profit |
| Krios data collection per 24 hours (full service) | $2,848.29 | industry | commercial; staff does imaging |
| Krios per 24 hours (self-use) | $2,222.02 | industry | commercial |